Über 80% neue Produkte zum Festpreis; Das ist das neue eBay. Finde ‪Medizinisches‬! Riesenauswahl an Markenqualität. Folge Deiner Leidenschaft bei eBay Bei uns finden Sie passende Fernkurse für die Weiterbildung von zu Hause Matched Pair-Analyse zwischen Aus der Klinik für Orthopädie und Rheumatologie des Fachbereiches Medizin der Philipps-Universität Marburg in Zusammenarbeit mit dem Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg Direktorin: Frau Univ.-Prof. Dr. med. Susanne Fuchs-Winkelman
Beurteilung, Auswertung und Publikation von prospektiven Matched-Pairs-Studien Eine bewährte Methode zur Erreichung der Vergleichbarkeit zweier Gruppen in prospektiven Beobachtungsstudien ist die Matched-Pair-Bildung, wie sie in den epidemiologischen Studien von Grossarth-Maticek angewandt wurde Matched-Pair-Analyse: Intensitätsmodulierte Radiotherapie (IMRT) versus 3D- konformale Radiotherapie. Akut- und Spättoxizität der Bestrahlung von Patienten mit Prostatakarzinom Darüber hinaus führen wir, als wissenschaftliche Mitarbeiter und Mediziner der DKMS, eigene Studien im Bereich Stammzellspende und -transplantation durch, um die Sicherheit und Erfolgschancen von Stammzellenspenden noch weiter zu verbessern. Eine solche Studie ist auch das so genannte Matched Pair-Spendernachbeobachtungsprogramm Hierzu wurden die NCB-Platte (polyaxial), sowie die PHILOS-Platte (monoaxial) ausgewählt. Als Design für diese Studie wurde eine Matched Pair-Analyse gewählt in die insgesamt 76 Patienten (=38 Paare) eingeschlossen werden konnten. Matching-Kriterien waren das Alter und Geschlecht der Patienten, sowie der Frakturtyp nach AO-Klassifikation (Weitergeleitet von Matched Pairs) Ein Paarvergleich ist eine Vergleichsmethode, bei der einzelne Objekte paarweise verglichen werden. Im Gegensatz dazu wird bei der Skalierung bzw. Ranking jedes Objekt einzeln betrachtet und auf einer Skala einsortiert
Aufgabe 10: Fall-Kontroll-Studien − Matched-Pairs-Technik Warum wird bei einigen Fall-Kontroll-Studien die Matched-Pairs-Technik angewandt?. Um gleich große Gruppen zu erhalten. Um Strukturgleichheit zu erreichen. Um Beobachtungsgleichheit zu erreichen Typisches Beispiel für Paare sind Untersuchungen, die jeweils an einem Auge oder einem Arm derselben Person durchgeführt werden. Typisch für verbundene Designs sind auch Vergleich vor und nach.. Matching bzw. deutsch paarweise Zuordnung bezeichnet in der Statistik Methoden, mit denen ähnliche Beobachtungen in zwei oder mehr Datensätzen verbunden werden. Mit Matching-Methoden wird anhand gemeinsamer Merkmale den Beobachtungen aus einem Datensatz eine oder mehrere ähnliche Beobachtungen aus den anderen Datensätzen zugeordnet MEDIZIN: Übersichtsarbeit Propensity Score - eine alternative Methode zur Analyse von Therapieeffekten Teil 23 der Serie zur Bewertung wissenschaftlicher Publikatione
Matched Square Pairs, an extension of MMP analysis, can allow a judgement of the quality of generalized relationships. By looking at squares (pairs of matched-pairs) it is possible to check for non-additivity and for outliers. The matched square shows four transforms, which could involve a change of the core and two R-groups or one core and three R-groups as shown i Matched molecular pair analysis (MMPA) is a method in cheminformatics that compares the properties of two molecules that differ only by a single chemical transformation, such as the substitution of a hydrogen atom by a chlorine one. Such pairs of compounds are known as matched molecular pairs (MMP). Because the structural difference between the two molecules is small, any experimentally. Pairwise comparison generally is any process of comparing entities in pairs to judge which of each entity is preferred, or has a greater amount of some quantitative property, or whether or not the two entities are identical.The method of pairwise comparison is used in the scientific study of preferences, attitudes, voting systems, social choice, public choice, requirements engineering and.
Manatunga A, Oakes D: Parametric analysis for matched pair survival data. Lifetime Data Anal. 1999, 5: 371-387. 10.1023/A:1009692210273. Mehrotra D, Su S, Li X: An efficient alternative to the stratified cox model analysis. Stat Med. 2012, 31: 1849-1856. 10.1002/sim.5327. Article PubMed Google Scholar 27. Katsahian S, Latouche A, Mary J, Chevret S, Porcher R: Practical methodology of meta. Protektive Stentimplantation nach erfolgreicher Rekanalisation von chronischen Koronarverschlüssen: Eine Matched-Pair-Analyse in 100 Patienten Zeitschrift: Clinical Research in Cardiology > Ausgabe 12/1998 Autoren: S. Fratz, T. Meinertz, C.A. Nienabe
In the seventh randomised matched-pair study (22 pairs, melanoma [...] without metastases) there was a trend showing that survival time in patients treated with mistletoe therapy was longer (hazard rate 0.47, 95% confidence interval: 0.19-1.14) and the time to event was significantly longer (hazard rate 0.49; 95% confidence interval 0.32-0.75) compared to control group Matched pair-analysis. Each foreign patient was matched with one German control patient in a fashion blinded to patients' outcomes. The criteria for the matching process were defined as follows: Diagnosis (based on ICD-10 and ICD-O-3), disease status (primary case vs. recurrence), tumor stage (UICC status for solid tumors, Ann-Arbor status for lymphomas, Durie and Salmon status for multiple. A matched molecular pair (MMP) analysis was used to examine the change in melting point (MP) between pairs of similar molecules in a set of ∼275k compounds. We found many cases in which the change in MP (ΔMP) of compounds correlates with changes in functional groups. In line with the results of a previous study, correlations between ΔMP and simple molecular descriptors, such as the number. The study was performed as a matched-pair-analysis, where patients of the two treatment groups were required to individually match for nine factors. Since another randomized trial would be difficult to perform, a matched-pair study is the best alternative design to reduce the risk of selection biases. Patients and methods. A total of 252 patients with a Karnofsky performance score (KPS) of.
matched-pair analysis, with 16 of them being primary kidney-transplanted patients and 20 primary liver trans-planted patients. Five patients with PTLD were excluded due to the lack of available data on important risk fac-tors or inability to find an appropriate matching case without PTLD during follow-up. Within the group of 16 kidney-transplanted patients, nine were female and seven were male. Med. Chem. 2011, 54 (22), pp.7739-7750. 3 Leach, A.G. et. al. Matched Molecular Pairs as a Guide in the Optimization of Pharmaceutical Properties; a Study of Aqueous Solubility, Plasma Protein Binding and Oral Exposure However, the study was based on matched-pair analyses of only 58 male breast carcinomas and three matching criteria (age, year of diagnosis, stage). Tumor differentiation, hormone receptor status and HER2 positivity were not considered. This might reflect an incomplete matching procedure and could better explain the divergent findings to our results. Conclusion. Our retrospective study showed. Pharmacophore extraction from Matched Molecular Pair Analysis MedChemica publishes J Med Chem paper on building a massive rule database for medicinal chemistry. January 18th, 2018 | 0 Comments. News. SpotDesign: MedChemica's Multiparameter ADMET optimisation tool is now available; MedChemica quick read: AI, Big Data and the Medicinal Chemist now online. MedChemica publishes Drug.
The case-control matching procedure is used to randomly match cases and controls based on specific criteria. MedCalc can match on up to 4 different variables. In the example we will use the following data: The treated cases are coded 1, the controls are coded 0. For each treated case MedCalc will try to find a control case with matching age and. analysis—part 14 of a series on evaluation of scientific publications. Dtsch Arztebl Int 2010; 107(44): 776-82. DOI: 10.3238/arztebl.2010.0776 Bei statistischen Auswertungen von medizini-schen Daten besteht das Ziel oft darin, Zusam-menhänge zwischen zwei oder mehreren Variablen zu beschreiben. Es ist beispielsweise nicht nur interes-sant, ob Patienten einen erhöhten Blutdruck haben. DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.. Mismatch repair is strand-specific. During DNA synthesis the newly synthesised (daughter) strand will commonly include errors Das IQWiG untersucht als unabhängiges wissenschaftliches Institut im Auftrag des Gemeinsamen Bundesausschusses oder des Bundesgesundheitsministeriums den Nutzen medizinischer Leistungen für den Patienten. Neben der Vorstellung der Arbeitsbereiche und der bearbeiteten Projekte finden sich eine Übersicht über Publikationen sowie ein Bereich mit Pressematerialien
A matched-pair analysis has been performed at the Centre for Reproductive Medicine of the UZ Brussel, Dutch speaking Free University of Brussel. A total of 410 pregnancies resulted in birth beyond 20 weeks of gestation occurring over a period of 10 years, including 205 oocyte donation pregnancies and 205 ICSI pregnancies with autologous oocytes. Therefore, only patients who, in retrospect, would not have required intubation were included in the matched-pairs analysis to evaluate the risks related to intubation. Methods The data of 42,248 patients taken from the trauma registry of the German Association for Trauma Surgery (Deutsche Gesellschaft für Unfallchirurgie (DGU)) were analyzed
Matched pair criteria (age, presence of an accompanying meniscus tear or cartilage injury, additional meniscus or cartilage surgery), the surgeon performing the operation (senior author J.H.), graft selection (patients were free to choose the desired graft), the surgical techniques and the rehabilitation protocol were identical to the studies published in the apron [23, 28] Patients with. To set up the analysis we first need to specify which pairs of variables we want to add to the analysis. We only have one sensible pair available here - but if we had more, we could run multiple t-tests simultaneously. For this example we want to compare the scores in the black_errors and white_errors conditions. To start the analysis, SELECT the both of these conditions (while holding down.
Purpose:Athletes often receive conservative treatment for injured anterior cruciate ligaments (ACLs) so that they can continue to play to the end of their season. The purpose of this study was to e.. A matched-pair analysis comparing 5x4 Gy and 10x3 Gy for metastatic spinal cord compression (MSCC) in patients with favorable survival prognoses. Dirk Rades 1, Stefan Huttenlocher 1, Theo Veninga 2, Amira Bajrovic 3, Michael Bremer 4, Volker Rudat 5 & Steven E Schild 6 Radiation Oncology volume 10, Article number: 90 (2015) Cite this article. 1716 Accesses. 2 Citations. 4 Altmetric. Metrics. Matched-Molecular Pair (MMP) analysis has recently emerged as a data analysis technique in medicinal chemistry. It quickly gained scientific momentum because it tackles key questions in lead optimization. In contrast to classical global QSAR models that attempt to predict the absolute numbers of ADME (absorption, distribution, metabolism, excretion) and toxicological properties, MMP analyses. Abstract - Multiple parameter optimisation in drug discovery is difficult, but Matched Molecular Pair Analysis (MMPA) can help. Computer algorithms can process data in an unbiased way to yield design rules and suggest better molecules, cutting the number of design cycles. The approach often makes more suggestions than can be processed manually and methods to deal with this are proposed.
Methods: A matched-pair analysis has been performed at the Centre for Reproductive Medicine of the UZ Brussel, Dutch speaking Free University of Brussel. A total of 410 pregnancies resulted in birth beyond 20 weeks of gestation occurring over a period of 10 years, including 205 oocyte donation pregnancies and 205 ICSI pregnancies with autologous oocytes (AO). Patients in the OD group were. Perineal trauma during childbirth affects millions of women worldwide every year. The aim of the Perineal Assessment and Repair Longitudinal Study (PEARLS) was to improve maternal clinical outcomes following childbirth through an enhanced cascaded multiprofessional training program to support implementation of evidence-based perineal management. This was a pragmatic matched-pair cluster.
Network meta-analysis, in the context of a systematic review, is a meta-analysis in which multiple treatments (that is, three or more) are being compared using both direct comparisons of interventions within randomized controlled trials and indirect comparisons across trials based on a common comparator. To ensure validity of findings from network meta-analyses, the systematic review must be. Single-nucleotide polymorphisms may fall within coding sequences of genes, non-coding regions of genes, or in the intergenic regions (regions between genes). SNPs within a coding sequence do not necessarily change the amino acid sequence of the protein that is produced, due to degeneracy of the genetic code.. SNPs in the coding region are of two types: synonymous and nonsynonymous SNPs
Szaki et al. Emerg Themes Epidemiol DOI10.1186/12982-017-0060-8 ANALYTICPERSPECTIVE Od ratio estimators by˜proportional hazards models in˜matched -pair cohort studies Tomohiro Shinozaki1*,Mohammad Ali Mansournia2and Yutaka Matsuyama1 Abstrac According to the Louisville Statement, laparoscopic major hepatectomy is a heterogeneous category that includes traditional trisectionectomies/hemi. matching pairs that had comparable gender, age, severity of traumatic brain injury, initial GCS, presence/absence of shock. To create two study groups, one partner of every pair had additional thoracic injuries of varying de-grees (i.e. AIS Thorax =2, 3, 4 or 5) (Fig. 1). Matching pairs were included in the statistical analysi Etanercept has been approved in polyarticular juvenile idiopathic arthritis (JIA) patients refractory or intolerant to methotrexate. The objectives of the study were to evaluate safety and efficacy of Etanercept and Methotrexate combination therapy versus Etanercept mono therapy in JIA using a matched pair analysis Unsere Bestenliste 10/2020 - Ausführlicher Test Ausgezeichnete Cord Schlaghose Bester Preis Preis-Leistungs-Sieger - JETZT direkt weiterlesen
The sensitivity analysis (702 pairs of the matching) showed a significantly higher survival rate in the closed ICU (71.8% vs 65.2%, p = 0.011). The length of ICU stay of patients in closed ICUs was significantly shorter (20% less). This Japanese nationwide analysis of patients with sepsis shows a significant association between treatment in a.